个人简介:
姓 名:庞雪辉 导师类型:硕导
技术职务:教授 专业/学历:博士
电子邮箱:pxh1118@126.com
工作及教育经历:
2019.05-2023.05: 山东师范大学
2007.09-2019.04: 济南大学
2004.09-2007.06:中国海洋大学,理学博士
2001.09-2004.06:山东师范大学,理学硕士
1997.09-2001.06:山东师范大学,理学学士
科研与学术工作经历:
2017.02-2018.02: 美国佛罗里达大学 访问学者 合作导师:谭蔚泓院士
2009.05-2012.06: 中国科学院海洋研究所 博士后 合作导师:侯保荣院士
研究方向
研究方向一:癌症即时诊断仪器开发;
研究方向二:医学应用领域的AI数字模拟
研究方向三:医学相关数字、图像信号处理
主持项目:
国家自然科学青年基金“用于外泌体一体化分离、检测的自供能微流控检测器的研制(21904081),2020.1-2022.12
国家科技支撑计划协作课题(wbs0623),2008-2010
山东省重点研发计划(2015GGH301001),2015.3-2018.2
山东省自然科学基金面上项目(ZR2019MB059),2019.07-2022.06
山东省高等学校科研计划项目(J15LC07),2015.5-2018.2
中国博士后面上项目(2016M592125),2016.1-2017.9
中国博士后科学基金特别资助(201003655),2009-2011
中国博士后面上项目(20090461269),2009-2011
山东省自然科学基金(ZR2011EMQ010),2012-2014
山东省博士后自主创新项目(200902040),2009-2010
四川省教育厅科研项目(2010cl06), 2010-2012
化学生物传感与计量学国家重点实验室(湖南大学)开放课题(2018018),2018-2020
中国科学院海洋研究所开放课题(W11037),2010-2012
中国科学院海洋研究所开放课题(200901005),2009-2011
参与项目:
天津市顶尖科学家工作室项目“基于省部共建分离膜与膜过程国家重点实验室的顶尖科学家工作室项目(24JRRCRC00040),2024.01-2027.01
国家自然科学基金面上项目(21777056) 2017.1-2021.12
国家自然科学基金面上项目(21375047),2014.1-2017.12
国家自然科学基金青年项目(21607503),2016.1-2018.12
国家自然科学基金青年项目(21405059),2014.1-2016.12
国家自然科学基金面上项目(21075052), 2010.1-2013.12
国家自然科学基金面上项目(21175057) 2011.1-2014.12
山东省科技发展计划项目(2008GG10005016),2007-2009
山东省自然科学基金面上项目 (ZR2010BM030),2010-2013
山东省自然科学基金面上项目(Y2007E13),2007-2009
获奖情况:
2018年 山东省高等学校科研成果奖二等奖
2018年 山东医学科技奖二等奖
2017年 济南大学优秀科技成果奖二等奖
2017年 中国商业联合会科学技术奖一等奖
2016年 中国商业联合会科学技术奖特等奖
2016年 本科教学贡献奖
2015年 山东省科技进步奖二等奖
2015年 中国商业联合会科学技术奖一等奖
2015年 济南大学教学研究成果一等奖
教研项目
校级教学改革项目面上项目,2020.9-2021.12
校级研究生精品课程建设项目,2017.1-2018.12
校级重点教学改革项目(JZ1408),2015.1-2017.10
校级教研项目,2014.1-2015.12
校级重点教学改革项目(JZ1210),2012.10-2014.10
校级百门课程改革,2011.9-2013.9,结题A级
校级教研项目,2011.12-2013.1,第一位
校级教研项目,2010.12-2012
学生指导工作
指导学生多次获得校级优秀论文(2009/2011/2013/2015-2018/2021)
国家级大学生创新创业训练计划项目,2022.6-2023.12
国家级大学生创新创业训练计划项目,2016.1-2017.6
校级创新训练项目,2016.11-2017.6
校级创新训练项目, 2016.9-2017.5
校级创新训练项目, 2010.4-2011.3
校级创新训练项目2014.10-2015.5
校级大学生首届科技创新大赛,2014.9-2015.2,二等奖
校级创新训练项目,2015.9-2016.5
校级创新训练项目,2011.4-2012.3
所指导本科生依托所得成果获得2016-2017学年本科生国家奖学金2人次,多人考取985、211名校
代表性学术论文:
Gao, Ning, Zhang, Yifeng, Gao, Keke, Xie, Jiandong, Liu, Lei, Li, Yuyang, Qiu, Liping, Wei, Qin*, Ma, Hongmin*, Pang, Xuehui*, Ultrasensitive label-free photoelectrochemical immunosensor for the detection of amyloid beta-protein based on Zn:SnO2/SnS2-Au nanocomposites. Sensors and Actuators B-Chemical 2020, 308.(一区,9.221)
Pang, Xuehui, Zhang, Xin, Gao, Keke, Wan, Shuo, Cui, Cheng, Li, Lu, Si, Haibin, Tang, Bo*, Tan, Weihong*, Visible Light-Driven Self-Powered Device Based on a Straddling Nano-Heterojunction and Bio-Application for the Quantitation of Exosomal RNA. ACS Nano 2019, 13 (2), 1817-1827.(一区,18.027)
Pang, Xuehui, Cui, Cheng, Su, Minhui, Wang, Yaoguang, Wei, Qin*, Tan, Weihong*, Construction of self-powered cytosensing device based on ZnO nanodisks@g-C3N4 quantum dots and application in the detection of CCRF-CEM cells. Nano Energy 2018, 46, 101-109.(一区,19.069)
Li, Xiaojian, Lu, Peng, Wu, Bin, Wang, Yaoguang, Wang, Huan, Du, Bin*, Pang, Xuehui*, Wei, Qin*, Electrochemiluminescence quenching of luminol by CuS in situ grown on reduced graphene oxide for detection of N-terminal pro-brain natriuretic peptide. Biosensors & Bioelectronics 2018, 112, 40-47.(一区,12.545)
Xu, Rui, Lu, Peng, Wu, Bin, Wang, Xueping, Pang, Xuehui, Du, Bin, Fan, Dawei, Wei, Qin*, Using SiO2/PDA-Ag NPs to dual-inhibited photoelectrochemical activity of CeO2-CdS composites fabricated a novel immunosensor for BNP ultrasensitive detection. Sensors and Actuators B-Chemical 2018, 274, 349-355.(一区,9.221)
Wang, Chao, Zhu, Wenjuan, Yan, Tao, Yang, Lei, Kuang, Xuan, Du, Bin, Pang, Xuehui*, Wei, Qin*, Novel electrochemiluminescent platform based on gold nanoparticles functionalized Ti doped BiOBr for ultrasensitive immunosensing of NT-proBNP. Sensors and Actuators B-Chemical 2018, 277, 401-407.(一区,9.221)
Wang, Yaoguang, Zhao, Guanhui, Zhang, Yong, Pang, Xuehui*, Cao, Wei, Du, Bin*, Wei, Qin*, Sandwich-type electrochemical immunosensor for CEA detection based on Ag/MoS2@Fe3O4 and an analogous ELISA method with total internal reflection microscopy. Sensors and Actuators B-Chemical 2018, 266, 561-569.(一区,9.221)
Wang, Yaoguang, Wang, Yulan, Wu, Dan, Ma, Hongmin, Zhang, Yong, Fan, Dawei, Pang, Xuehui*, Du, Bin*, Wei, Qin*, Label-free electrochemical immunosensor based on flower-like Ag/MoS2/rGO nanocomposites for ultrasensitive detection of carcinoembryonic antigen. Sensors and Actuators B-Chemical 2018, 255, 125-132.(一区,9.221)
Pang, Xuehui, Cui, Cheng, Wan, Shuo, Jiang, Ying, Zhang, Liangliang, Xia, Lian, Li, Long, Li, Xiaowei, Tan, Weihong*, Bioapplications of Cell-SELEX-Generated Aptamers in Cancer Diagnostics, Therapeutics, Theranostics and Biomarker Discovery: A Comprehensive Review. Cancers 2018, 10 (2), 47-64.(二区,6.575)
Jin, Cheng, Liu, Xiaojing, Bai, Huarong, Wang, Ruowen, Tan, Jie, Pang, Xuehui, Tan, Weihong*, Engineering Stability-Tunable DNA Micelles Using Photocontrollable Dissociation of an Intermolecular G-Quadruplex. ACS Nano 2017, 11 (12), 12087-12093.(一区,18.027)
Shi, Li, Li, Xiaojian, Zhu, Wenjuan, Wang, Yaoguang, Du, Bin, Cao, Wei, Wei, Qin*, Pang, Xuehui*, Sandwich-Type Electrochemiluminescence Sensor for Detection of NT-proBNP by Using High Efficiency Quench Strategy of Fe3O4@PDA toward Ru(bpy)32+ Coordinated with Silver Oxalate. ACS Sensors 2017, 2 (12), 1774-1778.(一区,9.618)
Yang, Lei, Li, Yueyuan, Zhang, Yong, Fan, Dawei, Pang, Xuehui, Wei, Qin, Du, Bin*, 3D Nanostructured Palladium-Functionalized Graphene-Aerogel-Supported Fe3O4 for Enhanced Ru(bpy)32+-Based Electrochemiluminescent Immunosensing of Prostate Specific Antigen. ACS Applied Materials & Interfaces 2017, 9 (40), 35260-35267.(一区,10.383)
Ren, Xiang, Zhang, Tong, Wu, Dan, Yan, Tao, Pang, Xuehui, Du, Bin, Lou, Wanruo, Wei, Qin*, Increased electrocatalyzed performance through high content potassium doped graphene matrix and aptamer tri infinite amplification labels strategy: Highly sensitive for matrix metalloproteinases-2 detection. Biosensors & Bioelectronics 2017, 94, 694-700.(一区,12.545)
Pang, Xuehui, Bian, Hongjun, Wang, Weijie, Liu, Cheng, Khan, Malik Saddam, Wang, Qiao, Qi, Jianni, Wei, Qin*, Du, Bin*, A bio-chemical application of N-GQDs and g-C3N4 QDs sensitized TiO2 nanopillars for the quantitative detection of pcDNA3-HBV. Biosensors & Bioelectronics 2017, 91, 456-464(一区,12.545)
Pang, Xuehui, Bian, Hongjun, Su, Minhui, Ren, Yangyang, Qi, Jianni, Ma, Hongmin, Wu, Dan, Hu, Lihua, Du, Bin*, Wei, Qin*, Photoelectrochemical Cytosensing of RAW264.7 Macrophage Cells Based on a TiO2 Nanoneedls@MoO3 Array. Analytical Chemistry 2017, 89 (15), 7950-7957.(一区,8.008)
Wang, Yaoguang, Zhang, Yong, Wu, Dan, Ma, Hongmin, Pang, Xuehui, Fan, Dawei, Wei, Qin*, Du, Bin*, Ultrasensitive Label-free Electrochemical Immunosensor based on Multifunctionalized Graphene Nanocomposites for the Detection of Alpha Fetoprotein. Scientific Reports 2017, 7, 42361.(二区,4.996)
Pang, Xuehui, Qi, Jianni, Zhang, Yong, Ren, Yangyang, Su, Minhui, Jia, Baoxiu, Wang, Yaoguang, Wei, Qin*, Du, Bin*, Ultrasensitive photoelectrochemical aptasensing of miR-155 using efficient and stable CH3NH3PbI3 quantum dots sensitized ZnO nanosheets as light harvester. Biosensors & Bioelectronics 2016, 85, 142-150.(一区,12.545)
Pang, Xuehui, Zhang, Yong, Pan, Jihong, Zhao, Yanxia, Chen, Yao, Ren, Xiang, Ma, Hongmin, Wei, Qin*, Du, Bin*, A photoelectrochemical biosensor for fibroblast-like synoviocyte cell using visible light-activated NCQDs sensitized-ZnO/CH3NH3PbI3 heterojunction. Biosensors & Bioelectronics 2016, 77, 330-338.(一区,12.545)
Liu, Yixin, Ma, Hongmin, Zhang, Yong, Pang, Xuehui, Fan, Dawei, Wu, Dan, Wei, Qin*, Visible light photoelectrochemical aptasensor for adenosine detection based on CdS/PPy/g-C3N4 nanocomposites. Biosensors & Bioelectronics 2016, 86, 439-445.(一区,12.545)
Liu, Yixin, Zhang, Yifeng, Wu, Dan, Fan, Dawei, Pang, Xuehui, Zhang, Yong, Ma, Hongmin, Sun, Xu, Wei, Qin*, Visible-light driven photoelectrochemical immunosensor for insulin detection based on MWCNTs@SnS2@CdS nanocomposites. Biosensors & Bioelectronics 2016, 86, 301-307.(一区,12.545)
Wu, Dan, Wang, Yaoguang, Zhang, Yong, Ma, Hongmin, Pang, Xuehui, Hu, Lihua, Du, Bin*, Wei, Qin*, Facile fabrication of an electrochemical aptasensor based on magnetic electrode by using streptavidin modified magnetic beads for sensitive and specific detection of Hg2+. Biosensors & Bioelectronics 2016, 82, 9-13.(一区,12.545)
Liu, Yuanyuan, Ma, Hongmin, Gao, Jian, Wu, Dan, Ren, Xiang, Yan, Tao, Pang, Xuehui, Wei, Qin*, Ultrasensitive electrochemical immunosensor for SCCA detection based on ternary Pt/PdCu nanocube anchored on three-dimensional graphene framework for signal amplification. Biosensors & Bioelectronics 2016, 79, 71-78.(一区,12.545)
Lv, Xiaohui, Ma, Hongmin, Wu, Dan, Yan, Tao, Ji, Lei, Liu, Yixin, Pang, Xuehui, Du, Bin*, Wei, Qin*, Novel gold nanocluster electrochemiluminescence immunosensors based on nanoporous NiGd-Ni2O3-Gd2O3 alloys. Biosensors & Bioelectronics 2016, 75, 142-147.(一区,12.545)
Zhang, Yong, Pang, Xuehui, Wu, Dan, Ma, Hongmin, Yan, Zhaoqing, Zhang, Jiatao, Du, Bin*, Wei, Qin*, A robust electrochemiluminescence immunoassay for carcinoembryonic antigen detection based on a microtiter plate as a bridge and Au@Pd nanorods as a peroxidase mimic. Analyst 2016, 141 (1), 337-345.(二区,5.227)
Pang, Xuehui, Zhang, Yong, Liu, Cheng, Huang, Ya, Wang, Yaoguang, Pan, Jihong, Wei, Qin*, Du, Bin*, Enhanced photoelectrochemical cytosensing of fibroblast-like synoviocyte cells based on visible light-activated ox-GQDs and carboxylated g-C3N4 sensitized TiO2 nanorods. Journal of Materials Chemistry B 2016, 4 (26), 4612-4619.(二区,7.577)
Pang, Xuehui, Wang, Lin, Ma, Hongmin, Zhang, Yong, Pan, Jihong, Chen, Yao, Du, Bin*, Wei, Qin*, Enhanced photoelectrochemical aptasensing platform for TXNDC5 gene based on exciton energy transfer between NCQDs and TiO2 nanorods. Scientific Reports 2016, 6, 19202.(二区,4.996)
Yan, Zhaoqing, Ma, Hongmin, Fan, Dawei, Hu, Lihua, Pang, Xuehui, Gao, Jian, Wei, Qin*, Wang, Qi, An ultrasensitive sandwich-type electrochemical immunosensor for carcino embryonie antigen based on supermolecular labeling strategy. Journal of Electroanalytical Chemistry 2016, 781, 289-295.(三区,4.598)
Pang, Xuehui, Pan, Jihong, Gao, Picheng, Wang, Youying, Wang, Liguo, Du, Bin*, Wei, Qin*, A visible light induced photoelectrochemical aptsensor constructed by aligned ZnO@CdTe core shell nanocable arrays/carboxylated g-C3N4 for the detection of Proprotein convertase subtilisin/kexin type 6 gene. Biosensors & Bioelectronics 2015, 74, 49-58.(一区,12.545)
Pang, Xuehui, Pan, Jihong, Wang, Lin, Ren, Wei, Gao, Picheng, Wei, Qin*, Du, Bin*, CdSe quantum dot-functionalized TiO2 nanohybrids as a visible light induced photoelectrochemical platform for the detection of proprotein convertase subtilisin/kexin type 6. Biosensors & Bioelectronics 2015, 71, 88-97.(一区,12.545)
Wang, Yulan, Ma, Hongmin, Wang, Xiaodong, Pang, Xuehui, Wu, Dan, Du, Bi*, Wei, Qin*, Novel signal amplification strategy for ultrasensitive sandwich-type electrochemical immunosensor employing Pd-Fe3O4-GS as the matrix and SiO2 as the label. Biosensors & Bioelectronics 2015, 74, 59-65.(一区,12.545)
Gao, Jian, Guo, Zhankui, Su, Fengjie, Gao, Liang, Pang, Xuehui, Cao, Wei, Du, Bin*, Wei, Qin*, Ultrasensitive electrochemical immunoassay for CEA through host-guest interaction of beta-cyclodextrin functionalized graphene and Cu@Ag core-shell nanoparticles with adamantine-modified antibody. Biosensors & Bioelectronics 2015, 63, 465-471.(一区,12.545)
Ren, Xiang, Wu, Dan, Wang, Yuhuan, Zhang, Yunhui, Fan, Dawei, Pang, Xuehui, Li, Yueyun, Du, Bin*, Wei, Qin*, An ultrasensitive squamous cell carcinoma antigen biosensing platform utilizing double-antibody single-channel amplification strategy. Biosensors & Bioelectronics 2015, 72, 156-159.(一区,12.545)
Lv, Xiaohui, Li, Yueyun, Yan, Tao, Pang, Xuehui, Cao, Wei, Du, Bin, Wu, Dan*, Wei, Qin*, Electrochemiluminescence modified electrodes based on RuSi@Ru(bpy)32+ loaded with gold functioned nanoporous CO/Co3O4 for detection of mycotoxin deoxynivalenol. Biosensors & Bioelectronics 2015, 70, 28-33.(一区,12.545)
Gao, Jian, Guo, Zhankui, Yu, Siqi, Su, Fengjie, Ma, Hongmin, Du, Bin, Wei, Qin*, Pang, Xuehui, A novel controlled release system-based homogeneous immunoassay protocol for SCCA using magnetic mesoporous Fe3O4 as a nanocontainer and aminated polystyrene microspheres as a molecular gate. Biosensors & Bioelectronics 2015, 66, 141-145.(一区,12.545)
Han, Tongqian, Yan, Tao, Li, Yueyun, Cao, Wei, Pang, Xuehui, Huang, Qingjuan, Wei, Qin*, Eco-friendly synthesis of electrochemiluminescent nitrogen-doped carbon quantum dots from diethylene triamine pentacetate and their application for protein detection. Carbon 2015, 91, 144-152.(一区,11.307)
Pang, Xuehui, Li, Jianxiu, Zhao, Yongbei, Wu, Dan, Zhang, Yong, Du, Bin, Ma, Hongmin*, Wei, Qin*, Label-Free Electrochemiluminescent Immunosensor for Detection of Carcinoembryonic Antigen Based on Nanocomposites of GO/MWCNTs-COOH/Au@CeO2. ACS Applied Materials & Interfaces 2015, 7 (34), 19260-19267.(一区,10.383)
Lv, Xiaohui, Pang, Xuehui, Li, Yueyun, Yan, Tao, Cao, Wei, Du, Bin, Wei, Qin*, Electrochemiluminescent Immune-Modified Electrodes Based on Ag2Se@CdSe Nanoneedles Loaded with Polypyrrole Intercalated Graphene for Detection of CA72-4. ACS Applied Materials & Interfaces 2015, 7 (1), 867-872.(一区,10.383)
Wu, Dan, Xin, Xia, Pang, Xuehui, Pietraszkiewicz, Marek, Holyst, Robert, Sun, Xian'ge, Wei, Qin*, Application of Europium Multiwalled Carbon Nanotubes as Novel Luminophores in an Electrochemiluminescent Aptasensor for Thrombin Using Multiple Amplification Strategies. ACS Applied Materials & Interfaces 2015, 7 (23), 12663-12670.(一区,10.383)
Wang, Yulan, Wang, Yaoguang, Pang, Xuehui, Du, Bin, Li, He, Wu, Dan*, Wei, Qin*, Ultrasensitive sandwich-type electrochemical immunosensor based on dual signal amplification strategy using multifunctional graphenena nocomposites as labels for quantitative detection of tissue polypeptide antigen. Sensors and Actuators B-Chemical 2015, 214, 124-131.(一区,9.221)
Zhou, Jing, Han, Tongqian, Ma, Hongmin, Yan, Tao, Pang, Xuehui, Li, Yueyun*, Wei, Qin*, A novel electrochemiluminescent immunosensor based on the quenching effect of aminated graphene on nitrogen-doped carbon quantum dots. Analytica Chimica Acta 2015, 889, 82-89.(一区,6.991)
Li, Xiaojian, Guo, Zhankui, Li, Jianxiu, Zhang, Yong, Ma, Hongmin, Pang, Xuehui, Du, Bin*, Wei, Qin*, Quenched electrochemiluminescence of Ag nanoparticles functionalized g-C3N4 by ferrocene for highly sensitive immunosensing. Analytica Chimica Acta 2015, 854, 40-46.(一区,6.991)
Pang, XueHui*, Gong, Min, Zhang, YuXuan, Wei, Qin, Hou, BaoRong*, Corrosion inhibition and mechanism of mild steel in hydrochloric acid by ceftriaxone and amoxicillin. Science China-Chemistry 2011, 54 (9), 1529-1536.(一区,10.138)
Pang, Xuehui*, Ran, Xiangbin, Kuang, Fei, Xie, Jiandong, Hou, Baorong*, Inhibiting Effect of Ciprofloxacin, Norfloxacin and Ofloxacin on Corrosion of Mild Steel in Hydrochloric Acid. Chinese Journal of Chemical Engineering 2010, 18 (2), 337-345.(二区,3.898)
Pang XueHui*, Guo WenJuan, Li WeiHua, Xie JianDong, Liu FaQian, Hou BaoRong. Electrochemical, quantum chemical and SEM investigation of the inhibiting effect and mechanism of ciprofloxacin, norfloxacin and ofloxacin on the corrosion for mild steel in hydrochloric acid. Science China-Chemistry, 2008, 51(10), 928-936.(一区,10.138)
Pang, Xuehui, Hou, Baorong, Li, Weihua, Liu, Faqian, Yu, Zhigang*, 2,3,5-triphenyl-2H-tetrazolium chloride and 2,4,6-tri(2-pyridyl)-s-triazine on the corrosion of mild steel in HCl. Chinese Journal of Chemical Engineering 2007, 15 (6), 909-915.(二区,3.898)
代表性专利:
基于异质结光响应双通道传感芯片及其制备方法与应用,申请号:2021115898239
一种双功能标记物构建的免疫传感器用于分析物检测的方法。专利号:ZL201410171321.8
学术专著:
《海洋钢结构浪花飞溅区复层包覆防蚀技术》,副主编
《海洋钢筋混凝土腐蚀及修复补强技术》,科学出版社,编委